By Inge Scharrer, Wolfgang Schramm, G. Auerswald, A. Kurth, J. Oldenburg, W. Schramm, B. Zieger
This ebook includes the contribution to the thirty sixth Hemophilia Symposium, Hamburg 2005. the most subject matters are epidemiolgy, hemophilia treatment, orthopedic remedy in hemophiliacs, hemostaseologic prognosis and pediatric hemostaseology. the amount is rounded off via quite a few loose papers and posters on hemophilia, inhibitors in hemophilia and diagnostics.
Read Online or Download 36th Hemophilia Symposium Hamburg 2005: Epidemiology; Hemophilia Therapy - Management of Bleedings and Inhibitors; Orthopedic Treatment in Hemophiliacs; ... Pediatric Hemostaseology; Free Lectures PDF
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Extra resources for 36th Hemophilia Symposium Hamburg 2005: Epidemiology; Hemophilia Therapy - Management of Bleedings and Inhibitors; Orthopedic Treatment in Hemophiliacs; ... Pediatric Hemostaseology; Free Lectures
E. 9%) as shown in Table 2. 7% of patients with von Willebrand disease showed Ristocetin cofactor levels below 30% as demonstrated in Table 2. Table 2. 9% (19) of the patients with hemophilia B an inhibitor was found (see Table 2). These findings correspond to international large-scale prevalence studies and registry data indicating that the prevalence of inhibitors in the hemophiliac A population overall is up to 5% . Regarding data back to 1999 the inhibitor prevalence observed in our cohort is slightly declining as depicted in Figure 3.
3. Prevalence of patients with hemophilia A and inhibitors since 1999 rance therapies per year there is also no indication of an increasing prevalence of inhibitors in patients with hemophilia A. 5%) were infected with HIV. 6% of all HIV positive patients) Table 3. 0 HIV Infection and Causes of Death in Patients with Hemophilia in Germany 7 Fig. 4. Prevalence of patients with hemophilia A and inhibitors since 1978 (Presented at the Hamburg Hemophilia-Symposium) 8 H. Krebs, W. 3% of all HIV positive patients) that have up to now not shown severe symptoms (Table 3).
33% per year. 4%) died of other diseases not distinguished in this survey. No indications for Creutzfeldt-Jakob disease in our patient collective has been reported since. 1%) with no further comment have been reported. Table 4. 9 3 Died of other diseases 5 Died of accident. 7 28 100 HIV Infection and Causes of Death in Patients with Hemophilia in Germany Fig. 5a-f. Comparison total number of deaths of HIV, liver disease and cancer 9 10 H. Krebs, W. Schramm % of total numbers of deaths per year (a) (c) HIV (b) Liver disease Cancer total number of deaths per year Fig.