4D Modeling and Estimation of Respiratory Motion for by Paul Keall, Tokihiro Yamamoto, Yelin Suh (auth.), Jan

By Paul Keall, Tokihiro Yamamoto, Yelin Suh (auth.), Jan Ehrhardt, Cristian Lorenz (eds.)

Respiratory movement explanations a tremendous uncertainty in radiotherapy making plans of the thorax and top stomach. the most target of radiation remedy is to eliminate or reduce tumor cells with no destructive the encompassing tissue via supplying a excessive radiation dose to the tumor quarter and a dose as little as attainable to fit organ tissues. assembly this call for continues to be a problem specifically in case of lung tumors because of breathing-induced tumor and organ movement the place movement amplitudes can degree as much as a number of centimeters. accordingly, modeling of respiration movement has turn into more and more vital in radiation treatment. With 4D imaging innovations spatiotemporal photograph sequences might be obtained to enquire dynamic approaches within the patient’s physique. additionally, photograph registration permits the estimation of the breathing-induced movement and the outline of the temporal swap in place and form of the constructions of curiosity by means of setting up the correspondence among photographs received at assorted levels of the respiring cycle. In radiation remedy those movement estimations are used to outline actual remedy margins, e.g. to calculate dose distributions and to improve prediction versions for gated or robot radiotherapy. during this ebook, the expanding function of photo registration and movement estimation algorithms for the translation of complicated 4D clinical picture sequences is illustrated. diversified 4D CT photo acquisition strategies and conceptually assorted movement estimation algorithms are offered. The medical relevance is verified via instance purposes that are relating to the radiation treatment of thoracic and belly tumors. The state-of-the-art and views are proven by way of an perception into the present box of study. The publication is addressed to biomedical engineers, scientific physicists, researchers and physicians operating within the fields of scientific snapshot research, radiology and radiation therapy.

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Phys. 36(6), 2762 (Abstract) (2009) Part I 4D Image Acquisition Chapter 2 Helical 4D CT and Comparison with Cine 4D CT Tinsu Pan Abstract 4D CT was one of the most important developments in radiation oncology in the last decade. Its early development in single slice CT and commercialization in multi-slice CT has radically changed our practice in radiation treatment of lung cancer, and has enabled the stereotactic radiosurgery of early stage lung cancer. In this chapter, we will document the history of 4D CT development, detail the data sufficiency condition governing the 4D CT data collection; present the design of the commercial helical 4D CTs from Philips and Siemens; compare the differences between the helical 4D CT and the GE cine 4D CT in data acquisition, slice thickness, acquisition time and work flow; review the respiratory monitoring devices; and understand the causes of image artifacts in 4D CT.

Novel breathing motion model for radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. : A comparison between amplitude sorting and phase-angle sorting using external respiratory measurement for 4D CT. Med. Phys. : Comparative analysis of different scintigraphic approaches to assess pulmonary ventilation. J. Aerosol. Med. : Distribution of pulmonary ventilation using Xeenhanced computed tomography in prone and supine dogs. J. Appl. Physiol. : The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery.

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