Assessing antiviral potency of anti-HIV therapies in vivo by by Ding A.A., Wu H.

By Ding A.A., Wu H.

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Measures of obsessive–compulsive symptoms, worry, and depressive cognition are highly correlated in both clinical and nonclinical samples, and there is considerable similarity in the phenomenological profile of the three types of cognition (Clark, 2002). How can these cognitive phenomena be differentiated so that a precise treatment plan can be formulated? , involving thoughts more than images) that is focused primarily on the actual or potential nonachievement of goals in important life spheres (Borkovec, 1994; M.

This suggests that religious experience can have an inf luence on the content and experience of obsessional symptoms. Presence of depression and other personal experiences may also inf luence the content of obsessional ideation. Preoccupation with aggression may be evident in obsessional patients with a primary depressive disorder (Rachman & Hodgson, 1980). The onset of an obsessional episode may be preceded by certain traumatic or critical incidents that are thematically related to the content of the obsession (de Silva & Marks, 1999; Rhéaume, Freeston, Léger, & Ladouceur, 1998).

3. Criteria for Distinguishing between Normal and Abnormal Obsessions Normal obsessions Abnormal obsessions Less frequent Less unacceptable/distressing Little associated guilt Less resistance to the intrusion Some perceived control More frequent More unacceptable/distressing Significant feelings of guilt Strong resistance to the intrusion Diminished perceived control over the obsession Considered highly meaningful, threatening important core values of the self (egodystonic) Time-consuming intrusions that dominate conscious awareness Heightened concern with thought control Strong focus on neutralizing distress associated with the obsession Significant interference in daily living Considered meaningless, irrelevant to the self Brief intrusions that fail to dominate conscious awareness Less concern with thought control Less emphasis on neutralizing distress Less interference in daily living 32 THE NATURE OF OCD Many of these dimensions of abnormality are fairly obvious and were identified in studies that directly compared patients with OCD and nonclinical subjects (Calamari & Janeck, 1997; Rachman & de Silva, 1978).

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