Interstitial Hyperthermia by G. M. Hahn (auth.), Dr. Leonore Handl-Zeller (eds.)

By G. M. Hahn (auth.), Dr. Leonore Handl-Zeller (eds.)

This ebook provides all powerful and secure innovations in interstitial hyperthermia and offers examples of purposes in components of scientific curiosity. Interstitial hyperthermia has been preferentially authorised by way of oncologists since it might be simply mixed with other kinds of therapy. one of many imperative merits is the threedimensionally limited warmth deposition to the tumor web site. The contributions during this ebook are written through specialists within the fields of biology, physics, and scientific implementation. The technical and scientific cutting-edge in addition to caliber insurance in interstitial hyperthermia is gifted and sensible details for the oncologists operating during this box is given.

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Cancer Res 40: 4728-4733 Chapman IV, Leyko W, Gaozdzinski K, Koter M, Grzelinska E, Bartosz G (1983) Hyperthermia modification of bleomycinDNA interaction detected by electron spine response. Radiat Res 96: 518522 Dahl 0, Mella (1982) Enhanced effect of combined hyperthermia and chemotherapy (bleomycin, BCNU) in a neurogenic rat tumour (BT4A) in vivo. Anticancer Res 2: 359-364 (1983) Effect of timing and Dahl 0, Mella sequence of hyperthermia and cyclophosphamide on a neurogenic rat tumor (BT4A) in vivo.

MEYN et al (1979) investigated the relationship between the production of strand breaks and cell survival, and reported that strand breaks produced at 43°C were more effective on cell-killing compared to those produced at 37°C. They further observed inhibition of the repair of strand breaks at 43°C while strand breaks produced at 37°C were rapidly repaired. CHAPMAN et al (1983) reported that DNA-BLM interaction was significantly higher at 43°C than at 37°C. SMITH et al (1986) demonstrated inhibition of the repair of DNA damage at 44°C.

Int J Radiat Biol 56: 801-811 Overgaard J, Biehel P (1977) The influenee of hypoxia and aeidity on the hyperthermie response of malignant eells in vitra. Radiology 123: 511-514 Overgaard J, Nielsen OS (1980) The role of tissue environmental faetors on the kineties and morphology of tumor eells exposed to hyperthermia. Ann NY Aead Sei 335: 254280 Overgaard J, Nielsen OS (1983) The importanee of thermotoleranee for the clinieal treatment with hyperthermia. Radiother Oneol1: 167-178 Overgaard J, Nielsen OS (1984) Influenee of thermotoleranee on the effeet of eombined hyperthermia and radiation in a C3H mammary eareinoma in vivo.

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